Influence of physiological and supraphysiological hyperinsulinemia on skin microcirculation in healthy volunteers

Table 2 Results are summarized in three groups

	Basal	50 mIU/L	150 mIU/L
Measured insulin level (mIU/L)	3.5	47.5b	144.5b
	(1.8-4.1)	(36.0-53.3)	(115.9-170.5)
LDF baseline (PU)	7.5	12.3	12.9
	(6.8-10.2)	(9.2-21.8)	(8.6-29.9)
LDF heating test (%)	1599	1848a	1937b
	(801-1836)	(984-2046)	(1177-2488)
LDF post-occlusion	4.9	1.2a	1.0b
Hyperemia test (s)	(1.8-11.4)	(0.9-2.6)	(0.7-1.1)
tcpO2 (mmHg)	38.9	48.6a	57.4a
	(35.5-40.8)	(45.5-49.7)	(51.7-66.2)

Data are expressed as median (interquartile range.

^aP < 0.05,

^bP < 0.01 vs basal group. LDF: Laser Doppler flowmetry.