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World J Diabetes. Dec 15, 2013; 4(6): 270-281
Published online Dec 15, 2013. doi: 10.4239/wjd.v4.i6.270
Published online Dec 15, 2013. doi: 10.4239/wjd.v4.i6.270
Table 2 Clinical characteristics of type 1, type 2 and MODY diabetes mellitus
Clinical characteristic | Type 1 diabetes mellitus | Type 2 diabetes mellitus | MODY diabetes mellitus |
Age when diagnosis is established | Preschool-adolescents | > 10 yr | MODY 2: youth |
MODY 3: adolescents | |||
Obesity | Uncommon1 | Common | Uncommon |
Gender | Male = female | Female > male | Male = female |
Relatives | 5% Type 1 D.m. | 75%-100% Type 2 D.m. | 100% MODY |
Population | Predominantly Caucasian | Predominantly Americans of African, Hispanic, Asian, and American Indian | |
b-cell autoantibodies | 85%-98% | Uncommon2 | Uncommon |
Insulin, C-peptide | Low | high | Low |
Ketoacidosis | Frequently | < 33% | Uncommon |
Associated disorders | Autoimmune disorders (thyroid, adrenal, vitiligo), celiac disease | Acanthosis nigricans | MODY 5: urogenital malformation |
PCOS | MODY 8: exocrine pancreas insufficency | ||
Metabolic Syndrome |
- Citation: Reinehr T. Type 2 diabetes mellitus in children and adolescents. World J Diabetes 2013; 4(6): 270-281
- URL: https://www.wjgnet.com/1948-9358/full/v4/i6/270.htm
- DOI: https://dx.doi.org/10.4239/wjd.v4.i6.270