Sequential elevation of autoantibodies to thyroglobulin and glutamic acid decarboxylase in type 1 diabetes

Table 1 Laboratory findings at the first visit

Laboratory findings
Urinalysis
Sugar	(-)
Protein	(-)
Ketone	(-)
Hematological data
WBC (/μL)	5.0 × 103
RBC (/μL)	4.5 × 106
Hb (g/dL)	13.1
Hct (%)	39.9
Plt (/μL)	21.7 × 104
Biochemical data
TP (g/dL)	6.6
AST (IU/L)	11
ALT (IU/L)	11
γ-GTP (IU/L)	10
TC (mg/dL )	184
TG (mg/dL )	50
Cr (mg/dL )	0.5
BUN (mg/dL )	14
PG (mg/dL )	100
HbA1c (%)	11.90
U-CPR (μg/d)	5.5
Immunological data
GAD65A (U/mL)	4342
IA-2A (index)	0.769
ZnT8A (index)	0.055
TPOAb (U/mL)	(-)
TGAb (U/mL)	(-)
HLA-DRB1	*03:01/*04:01
HLA-DQB1	*02:01/*03:02

HbA1c: Hemoglobin A1c; ZnT8A: Zinc transporter-8 autoantibodies; TPOAb: Thyroid peroxidase antibody; TGAb: Thyroglobulin antibody; WBC: White blood cell; RBC: Red blood cell; TP: Total protein; AST: Aspartate transaminase; ALT: Alanine aminotransferase; γ-GTP: γ-glutamyl transpeptidase; TC: Total cholesterol; TG: Triglyceride; Cr: Creatinine; BUN: Blood urea nitrogen; PG: Plasma glucose.