Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice

Figure 4 Effects of curcumin on adipose and liver malondialdehyde levels. A: Malondialdehyde levels in adipose tissue; B: Malondialdehyde levels in liver. The mice were fed with indicated diets and gavaged with curcumin or vehicle. At the end of 18 wk following normal diet (ND, n = 10), high fat diet (HFD, n = 6) and HFD + curcumin (n = 6) treatments, the mice were sacrificed, tissues were homogenized and malondialdehyde levels were measured as indicated in the “Materials and Methods”. ^aP < 0.001, HFD or HFD+curcumin vs ND. MDA: Malondialdehyde.