Role of nuclear factor erythroid 2-related factor 2 in negative pressure wound therapy for diabetic foot ulcers

Table 1 Comparison of the clinical characteristics between the two groups before treatment, n (%)

Variables	Control group (n = 21)	NPWT group (n = 19)	P value
Sex (male/female)	15/6	13/6	0.836
Smoking	9 (42.9)	8 (42.1)	0.962
Drinking	7 (33.3)	7 (36.8)	0.816
Wagner grade			1.000
2	4 (19.0)	3 (15.8)
3	11 (52.4)	10 (52.6)
4	6 (28.6)	6 (31.6)
Duration of diabetes (year)	12 (3, 18)	15 (12, 18)	0.615
Duration of diabetic foot (day)	14 (10, 15)	22 (7, 83)	0.486
Age (year)	61.19 ± 9.35	56.89 ± 9.40	0.107
FPG (mmol/L)	9.76 ± 3.65	9.95 ± 3.95	0.989
HbA1c (%)	10.52 ± 2.83	9.62 ± 3.11	0.316
Estimated glomerular filtration rate (mL/minute/1.73 m2)	111.72 ± 18.73	105.49 ± 16.94	0.261
Wound area (cm2)	13.12 ± 3.16	13.38 ± 3.16	0.978
Ankle brachial index	0.85 ± 0.08	0.84 ± 0.07	0.654
Average dressing frequency	8.67 ± 1.65	1.74 ± 0.87	0.000

FPG: Fasting plasma glucose; HbA1c: Glycated hemoglobin; NPWT: Negative pressure wound therapy.