Exercise training benefits pancreatic islet by modulating the insulin-like growth factor 1/phosphatidylinositol 3-kinase/protein kinase B pathway

Figure 5 Impact of diabetes and swimming training on the expression of phosphatidylinositol 3-kinase/protein kinase B. A: Determination of p-phosphatidylinositol 3-kinase (PI3K)/PI3K protein expression levels through Western blot (WB); B: Assessment of p-protein kinase B (AKT)/AKT protein expression levels through WB. ^aP < 0.05 vs the control sedentary group; ^dP < 0.05 vs the diabetic sedentary group. PI3K: Phosphatidylinositol 3-kinase; AKT: Protein kinase B; GADPH: Glyceraldehyde-3-phosphate dehydrogenase; D-Ex: The diabetic exercise group; D-Sed: The diabetic sedentary group; C-Ex: The control exercise group; C-Sed: The control sedentary group.