Role and mechanism of Roux-en-Y gastric bypass in the treatment of diabetic urinary bladder hyperactivity by reducing TRPV1 and P2X3

Figure 8 Detection of ATP and energy metabolism signaling pathways in mouse urine. A: Urine ATP standard curve; B: Statistical results of urine ATP content; C: Western blot representative images of energy signaling pathway proteins; D: Statistical results for phosphorylated AMP-activated protein kinase (p-AMPK); E: Statistical results for phosphorylated mammalian target of rapamycin (p-mTOR) (n = 8). ^aP < 0.05, overactive bladder (OAB) group compared with the sham group; ^bP < 0.05, Roux-en-Y gastric bypass (RYGB) compared with the OAB group.