MiR-29a-3p inhibits fibrosis of diabetic kidney disease in diabetic mice via downregulation of DNA methyl transferase 3A and 3B

Figure 5 Inhibition of DNA methyltransferase 3A/3B can reverse the effect of downregulation of miR-29a-3p on diabetic kidney disease-related fibrosis in SV40MES13 cells cultured with high glucose. Quantitative reverse transcription PCR detected the expression levels of alpha smooth muscle actin (α-SMA), collagen I, and fibronectin in the diabetic kidney disease model. Results are represented as mean ± SD (n = 3). ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. NC: Negative control.