Effect of systolic blood pressure status on coronary inflammation and high-risk plaque characteristics

doi:10.4239/wjd.v16.i4.102751

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Apr 15, 2025 (publication date) through Feb 28, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Apr 15, 2025; 16(4): 102751
Published online Apr 15, 2025. doi: 10.4239/wjd.v16.i4.102751

Table 4 Comparison of the coronary computed tomography angiography parameters between two groups of hypertension patients after matching, n (%)

	Low SBPV group vs high SBPV group			Controlled SBP group vs uncontrolled SBP group
	Low SBPV group, n = 191	High SBPV group, n = 191	P value	Controlled SBP group, n = 191	uncontrolled SBP group, n = 191	P value
Age (years)	64.21 ± 10.90	62.74 ± 9.88	0.168	63.72 ± 10.79	63.26 ± 9.86	0.653
Male sex	112 (58.6)	102 (53.4)	0.303	116 (55.8)	111 (53.4)	0.622
Body mass index (kg/m²)	24.40 ± 3.43	24.47 ± 3.88	0.862	24.39 ± 3.48	24.38 ± 3.79	0.953
Smoking	42 (22.0)	44 (23.0)	0.806	41 (19.7)	47 (22.6)	0.806
Dyslipidemia	83 (43.5)	82 (42.9)	0.918	93 (44.7)	93 (44.7)	1.000
Systolic pressure (mmHg)	136 ± 11	136 ± 13	0.876	-	-	-
SBPV (mmHg)	-	-	-	7.56 ± 1.64	9.07 ± 1.25	0.085
Statin	136 (71.2)	134 (70.2)	0.882	152 (73.1)	151 (72.6)	0.912
Tube voltage (kVp)			0.436			0.951
100	102 (53.4)	101 (52.9)		105 (50.5)	107 (51.4)
120	86 (45.0)	83 (43.5)		96 (46.2)	95 (45.7)
140	3 (1.6)	7 (3.7)		7 (3.4)	6 (2.9)
LAD-PCAT (HU)	-77.41 ± 7.50	-74.70 ± 8.86	0.002	-76.53 ± 7.67	-74.58 ± 8.57	0.016
LCX-PCAT (HU)	-70.95 ± 7.45	-70.18 ± 8.37	0.345	-70.39 ± 7.41	-69.67 ± 8.07	0.354
RCA-PCAT (HU)	-76.38 ± 7.81	-75.80 ± 8.59	0.496	-75.90 ± 7.81	-75.28 ± 8.62	0.381
High-risk plaques
Any LAP	51 (26.7)	84 (44.0)	< 0.001	54 (26.0)	97 (46.6)	< 0.001
Any SC	59 (30.9)	99 (51.8)	< 0.001	63 (30.3)	110 (52.9)	< 0.001
Any NRS	66 (34.6)	72 (37.7)	0.523	70 (33.7)	84 (40.4)	0.155
Any PR	117 (61.3)	155 (81.2)	< 0.001	123 (59.1)	171 (82.2)	< 0.001
OS	35 (18.5)	46 (28.6)	0.026	39 (18.9)	59 (33.1)	0.001

Data are showed as means ± SD, median (25^th and 75^th percentile), or n (%). SBP: Systolic blood pressure; SBPV: Systolic blood pressure variability; LAD: Left anterior descending artery; LCX: Left circumflex artery; RCA: Right coronary artery; PCAT: Pericoronary adipose tissue; NRS: Napkin-ring sign; SC: Spotty calcification; LAP: Low attenuation plaque; PR: Positive remodeling; OS: Obstructive stenosis.

Citation: Jiang CP, Liu YK, Cheng PP, Dong Y, Wang X, Wu FY, Xia YX, Wang PY, Xu XY. Effect of systolic blood pressure status on coronary inflammation and high-risk plaque characteristics. World J Diabetes 2025; 16(4): 102751
URL: https://www.wjgnet.com/1948-9358/full/v16/i4/102751.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i4.102751