Systematic review and critical appraisal of predictive models for diabetic peripheral neuropathy: Existing challenges and proposed enhancements

Table 4 Risk of bias and applicability assessment

Ref.	Risk of bias				Applicability			Overall
	Participants	Predictors	Outcome	Analysis	Participants	Predictors	Outcome	Risk of bias	Applicability
Ning et al[11]	+	-	+	-	-	+	+	-	-
Metsker et al[22]	-	-	+	-	+	+	+	-	+
Wu et al[17]	+	+	+	-	+	+	+	-	+
Fan et al[21]	-	-	+	-	+	+	+	-	+
Zhang et al[18]	+	-	-	-	+	+	+	-	+
Li et al[10]	-	-	+	-	+	+	+	-	+
Tian et al[20]	-	?	-	-	+	-	-	-	-
Li et al[15]	-	-	+	-	+	+	+	-	+
Lian et al[16]	-	+	+	-	+	+	+	-	+
Liu et al[19]	-	-	-	-	+	+	+	-	+
Wang et al[12]	+	+	+	-	+	+	+	-	+
Zhang et al[13]	+	-	+	-	-	+	+	-	-
Gelaw et al[14]	+	+	+	-	+	+	+	-	+
Baskozos et al[23]	-	-	+	-	+	+	+	-	+

ROB: Risk of bias; +: Low risk of bias/high concern regarding applicability; -: High risk of bias/low concern regarding applicability; ?: Unclear.