Association between serum retinol-binding protein and lower limb atherosclerosis risk in type 2 diabetes mellitus

Table 4 Subgroup analysis of relationship between serum retinol-binding protein level and lower limb atherosclerosis risk in type 2 diabetes mellitus patients

Subgroups	OR (95%CI)	P value	P for interaction
Age			0.019
< 60 years	1.01 (1.00, 1.02)	0.016
≥ 60 years	1.01 (0.99, 1.02)	0.400
Sex			0.700
Male	1.02 (1.01, 1.03)	0.003
Female	1.01 (0.99, 1.02)	0.500
BMI			0.900
< 25 kg/m2	1.01 (1.00, 1.02)	0.110
≥ 25 kg/m2	1.02 (1.00, 1.03)	0.011
Hypertension			0.800
Yes	1.01 (1.00, 1.02)	0.037
No	1.02 (1.00, 1.03)	0.036
Hyperlipidemia			0.700
Yes	1.01 (1.00, 1.02)	0.022
No	1.01 (1.00, 1.02)	0.091
CHD			0.200
Yes	1.03 (1.01, 1.06)	0.003
No	1.01 (1.00, 1.02)	0.069
eGFR			0.800
≤ 60 mL/minute/1.73 m2	1.02 (1.00, 1.03)	0.046
> 60 mL/minute/1.73 m2	1.01 (1.00, 1.02)	0.027

OR: Odds ratio; CI: Confidence interval; BMI: Body mass index; CHD: Coronary heart disease; eGFR: Estimated glomerular filtration rate. Adjusted for age, gender, body mass index, systolic blood pressure, diastolic blood pressure, cigarette smoking and alcohol consumption histories, hypertension, hyperlipidemia, coronary heart disease, fasting blood glucose, glycated hemoglobin, total cholesterol, triglycerides, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, aspartate aminotransferase, alanine aminotransferase, uric acid, C-reactive protein, white blood cell count, and estimated glomerular filtration rate; except the corresponding stratification variable.