Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat’s eyes

Figure 7 Glabridin and gymnemic acid have the capacity to enhance the choroid microvasculature feature. Scanning electron microscopy (SEM) micrographs with vascular corrosion casting technique/SEM in all five groups of rats. A: Control group; B: Diabetic group; C: Diabetic rats treated with glabridin 40 mg/kg body weight group; D: Diabetic rats treated with gymnemic acid 400 mg/kg body weight group; E: Diabetic rats treated with glyburide 4 mg/kg body weight group. The choroid artery (white roundness) splits into branches to supply the choroidal layer. Many anastomotic capillaries are what make up the choriocapillaris of the choroid (white arrowheads). In the diabetic group, choroid artery had a small diameter and the choriocapillaris shrank. The capillaries dropping out of the choriocapillaris (white arrow) were also present in diabetic group. Scale bar = 300 μm.