Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat’s eyes

Table 1 A comparison of blood glucose levels in different groups (mg/dL)

Week	C (mg/dL)	DM (mg/dL)	DM + GB (mg/dL)	DM + GM (mg/dL)	DM + GR (mg/dL)
1	70.5 ± 4.92	360.50 ± 32.331	314.83 ± 30.711	362.89 ± 49.291	297.67 ± 20.69
2	72.00 ± 5.49	290.50 ± 34.441	311.67 ± 49.731	269.22 ± 35.601	241.00 ± 36.433
3	79.17 ± 3.25	351.17 ± 43.251	305.33 ± 52.591	188.00 ± 41.511	176.50 ± 38.653
4	73.33 ± 3.57	253.67 ± 30.751	170.67 ± 41.11	240.89 ± 48.701	187.50 ± 45.61
5	72.00 ± 3.98	301.50 ± 55.411	137.00 ± 40.872	289.78 ± 50.062	192.50 ± 54.94
6	73.58 ± 3.55	351.00 ± 34.821	69.50 ± 13.693	249.78 ± 49.682	149.00 ± 47.483
7	73.00 ± 4.25	457.00 ± 20.991	158.33 ± 37.643	259.00 ± 45.532	165.83 ± 49.043
8	74.67 ± 3.31	353.83 ± 35.161	174.50 ± 30.993	213.44 ± 40.732	160.67 ± 52.463

¹P < 0.001 compared with control group.

²P < 0.01 compared with diabetic group.

³P < 0.001 compared with diabetic group.

C: Control; DM: Diabetic; DM + GB: Diabetic rats treated with glabridin 40 mg/kg body weight; DM + GM: Diabetic rats treated with gymnemic acid 400 mg/kg body weight; DM + GR: Diabetic rats treated with glyburide 4 mg/kg body weight.