O-linked β-N-acetylglucosamine transferase regulates macrophage polarization in diabetic periodontitis: In vivo and in vitro study

doi:10.4239/wjd.v16.i3.95092

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Mar 15, 2025 (publication date) through Feb 21, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Mar 15, 2025; 16(3): 95092
Published online Mar 15, 2025. doi: 10.4239/wjd.v16.i3.95092

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Figure 4 O-linked β-N-acetylglucosamine in diabetic periodontitis mice. A: Total O-linked β-N-acetylglucosamine levels in the maxillary bone of mice; B: Protein levels of O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) in the maxillary bone were detected using Western blot; C and D: Protein levels of OGT and OGA were quantified. ^aP < 0.05. P value calculated vs control. OGT: O-GlcNAc transferase; OGA: O-GlcNAcase; CON: Control; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.

Citation: Wu YK, Liu M, Zhou HL, He X, Wei J, Hua WH, Li HJ, Yuan QH, Xie YF. O-linked β-N-acetylglucosamine transferase regulates macrophage polarization in diabetic periodontitis: In vivo and in vitro study. World J Diabetes 2025; 16(3): 95092
URL: https://www.wjgnet.com/1948-9358/full/v16/i3/95092.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i3.95092