LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC

Figure 1 Differential expression of lnc-MGC and miR-495-3p in the diabetic retinopathy rat retina and cell model. A: Detection of lnc-MGC and miR-495-3p expression in diabetic retinopathy rat retina tissue by RT-qPCR; B: Expression levels of lnc-MGC and miR-495-3p in the cell model were detected by RT-qPCR; C: Localization of lnc-MGC in ARPE-19 cells was detected by fluorescence in situ hybridization (FISH). The scale bar represents 10 μm; D: Localization of miR-495-3p in ARPE-19 cells was detected by FISH. The scale bar represents 10 μm. ^aP < 0.001. NC: Normal control; DR: Diabetic retinopathy; HG: High glucose.