Role of duodenal mucosal resurfacing in controlling diabetes in rats

Figure 6 Metabolites and prospective metabolic pathways related to type 2 diabetes and the duodenal mucosal resurfacing procedure. A: Stacked bar chart of relative abundance statistics for the median values of various metabolites in the colonic contents of rats; B: Two-dimensional principal component analysis score map of colonic contents samples and corresponding box plot of principal component analysis scores; C: Bar chart of small molecule pathway database-associated metabolite sets used in the pathway enrichment analysis; D: Bubble chart of the rno library pathway analysis. ¹P < 0.05. ²P < 0.01. ³P < 0.001. DMR: Duodenal mucosal resurfacing; NC: Normal control; SCFA: Short-chain fatty acid; T2D: Type 2 diabetes; BAs: Bile Acids; PC1: Principal component 1; PC2: Principal component 2; TCA: Taurocholic acid.