Role of duodenal mucosal resurfacing in controlling diabetes in rats

Figure 2 Effects of the duodenal mucosal resurfacing procedure on phenotypic changes in type 2 diabetes rats. A-C: Body weight, food intake and fasting blood glucose throughout the experimental period after intraperitoneal injection of streptozotocin (n = 6 or 12 mice per group); D and E: Glucose excursion curves and the area under curve of oral glucose tolerance tests performed at postoperative weeks 3 (n = 12 mice per group) and 6 (n = 6 mice per group). Data are presented as mean ± SE. ¹P < 0.01 vs normal control group. ²P < 0.001 vs normal control group. ³P < 0.01 vs type 2 diabetes-sham group. ⁴P < 0.001 vs type 2 diabetes-sham group. DMR: Duodenal mucosal resurfacing; T2D: Type 2 diabetes; NC: Normal control; STZ: Streptozotocin; OGTT: Oral glucose tolerance test; AUC: Area under curve.