N6-methyladenosine methyltransferase Wilms tumor 1-associated protein impedes diabetic wound healing through epigenetically activating DNA methyltransferase 1

Figure 1 Wilms tumor 1-associated protein expression is elevated in high glucose-induced human umbilical vein endothelial cells. Human umbilical vein endothelial cells were stimulated with high glucose. A: Cell viability was measured using cell counting kit 8 assay; B: The in vitro angiogenesis was measured by tube formation assay; C: Cell migration was analyzed by Transwell assay; D: The relative RNA levels of RNA methyltransferases were measured by quantitative PCR assay. ^cP < 0.001; HG: High glucose; METTL3: Methyltransferase-like 3; WTAP: Wilms tumor 1-associated protein.