Overweight in mediating the association between depression and new-onset diabetes: A population-based research from Health and Retirement Study

Table 3 Mediation effect of overweight for depression to increased risk of new-onset diabetes

	β (SD)	OR (95%CI)	P value
Model A (overweight as the outcome)
Depression	0.18 (0.06)	1.20 (1.06-1.36)	0.004
Model B (new-onset diabetes as the outcome)
Overweight	1.13 (0.07)	3.10 (2.69-3.57)	< 0.001
Model C (new-onset diabetes as the outcome)
Depression	0.13 (0.07)	1.14 (1.00-1.30)	0.053
Sobel test for mediation effect			0.003

Model A was adjusted for the variables listed in the adjusted model in Table 2. Model B was further adjusted for depression in addition to the variables listed in the adjusted model in Table 2. Model C was further adjusted for overweight in addition to the variables listed in the adjusted model in Table 2. OR: Odds ratio; 95%CI: 95% confidence interval.