Effect of SPTLC1 on type 2 diabetes mellitus

Figure 3 Description of the mutation. A: The sanger sequence analysis of p.G371R mutation of SPTLC1 gene; B: Three dimensional (3D) structures of wild-type of human SPTLC1 gene; C: Structural formulas show that the mutant residue (R) is bigger than the wild-type residue (G); D: Zoomed 3D structure of mutation of human SPTLC1.