Transcriptome and single-cell profiling of the mechanism of diabetic kidney disease

Figure 3 The relationship between biomarkers and diabetic kidney disease. A: The relationship between biomarkers and diabetic kidney disease; B and C: Representative pathways enriched in the identified genes, as determined by gene set enrichment analysis (normal P < 0.05); D: Enrichment scores of differentially expressed immune cells between the two groups; E: Corrgrams showing the correlations between biomarkers and differential immune cells based on Pearson’s r values; F: Subcellular localization analysis of biomarkers; G: Chromosomal distribution of biomarkers. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; ^dP < 0.0001. KEGG: Kyoto Encyclopedia of Genes and Genomes; SIRT2: Sirtuin 2; CASP1: Caspase 1.