Risk factors for developing osteoporosis in diabetic kidney disease and its correlation with calcium-phosphorus metabolism, FGF23, and Klotho

Table 4 Logistic regression analysis of osteoporosis in diabetic kidney disease

Variable	B	Standard error	Standardization coefficient	t	P value
Lumbar bone mineral density
Constant	0.732	0.078		13.924	< 0.001
25-(OH)-D3	0.164	0.013	-0.372	8.942	< 0.001
iPTH	-0.329	0.030	0.201	7.995	< 0.001
blood Ca	0.228	0.017	0.101	10.424	< 0.001
Urinary phosphorus excretion fraction	-0.101	0.002	0.282	9.049	< 0.001
FGF23	-0.284	0.019	0.118	8.024	< 0.001
Klotho	0.118	0.005	-0.208	13.229	< 0.001
Age	-0.332	-0.032	-0.394	12.049	< 0.001
Gender	-0.492	0.074	-0.220	10.004	< 0.001
Bone mineral density of the left femoral neck
Constant	0.809	0.067		15.424	< 0.001
25-(OH)-D3	0.180	0.040	-0.394	8.492	< 0.001
iPTH	-0.364	0.038	0.233	6.824	< 0.001
Blood Ca	0.275	0.020	0.164	7.663	< 0.001
Urinary phosphorus excretion fraction	-0.128	0.008	0.840	5.312	0.003
FGF23	-0.295	0.042	0.175	4.990	0.007
Klotho	0.131	0.007	-0.232	9.402	< 0.001
Age	-0.347	-0.012	-0.384	8.448	< 0.001
Gender	-0.488	0.067	-0.214	7.940	< 0.001

iPTH: Intact parathyroid hormone; Ca: Calcium.