Risk factors for developing osteoporosis in diabetic kidney disease and its correlation with calcium-phosphorus metabolism, FGF23, and Klotho

Table 3 Correlation of calcium-phosphorus metabolic indexes with FGF23 and Klotho

	Normal (n = 55)				OP (n = 103)
	FGF23		Klotho		FGF23		Klotho
	r	P value	r	P value	r	P value	R	P value
25-(OH)-D3	−0.201	0.029	0.195	0.031	−0.342	< 0.001	0.356	< 0.001
iPTH	0.211	0.023	−0.205	0.028	0.352	< 0.001	−0.370	< 0.001
Blood Ca	−0.198	0.031	0.220	0.020	−0.364	< 0.001	0.377	< 0.001
Blood P	0.231	0.018	−0.221	0.020	0.337	< 0.001	−0.357	< 0.001
Calcium-phosphorus product	0.199	0.030	−0.035	0.774	0.384	< 0.001	−0.366	< 0.001
24-hour urinary phosphate excretion	−0.083	0.610	0.138	0.104	−0.379	< 0.001	0.401	< 0.001
Fractional excretion of phosphate	0.242	0.016	−0.244	0.015	0.338	< 0.001	−0.378	< 0.001

OP: Osteoporosis; iPTH: Intact parathyroid hormone; Ca: Calcium; P: Phosphorus.