Mizagliflozin ameliorates diabetes induced kidney injury by inhibitor inhibit inflammation and oxidative stress

Figure 3 Mizagliflozin decreases extracellular matrix and inflammation-related gene expression in diabetic mice. A: Collagen type 1 alpha 2 (COL1A2) mRNA level; B: COL1A1 mRNA level; C: Interleukin 1 beta mRNA level; D: Transforming growth factor beta mRNA level; E: Tumour necrosis factor alpha mRNA level; F: NF-E2-related factor-2 mRNA level. The values are presented as the mean ± standard error of the mean. ^aP < 0.05; ^bP < 0.01. MIZ: Mizagliflozin; COL1A2: Collagen type 1 alpha 2; IL: Interleukin; TGF: Transforming growth factor; TNF: Tumour necrosis factor; Nrf2: NF-E2-related factor-2.