Influence of gut bacteria on type 2 diabetes: Mechanisms and therapeutic strategy

Table 1 Mechanisms of specific gut microbiota species in influencing type 2 diabetes

Specific bacterial species		Influence path	Ref.
Beneficial bacteria	Lactobacillus	Improve the intestinal mucosal barrier function, enhance the immune function of the body, and promote the utilization of glucose by target organs	[22-24]
	Bifidobacterium	Maintain intestinal barrier function, reduce bacterial translocation, improve metabolic endotoxemia and reduce low level chronic inflammation	[25]
	Faecalibacterium prausnitzii	Produce butyrate, provide a balanced potential of hydrogen for the intestine	[26,27]
Harmful bacteria	Fusobacterium	Exacerbating the inflammatory state, produces 2HB	[28-31]
	Ruminococcus	Reduced short-chain fatty acids, helps the intestinal epithelial cells absorb sugar	[32-34]