Dexmedetomidine ameliorates diabetic intestinal injury by promoting the polarization of M2 macrophages through the MMP23B pathway

Figure 9 In vitro models demonstrated that GM6001 inhibits intestinal epithelium damage. A-F: Following lipopolysaccharide treatment, a substantial decrease was observed in the fluorescence intensity levels of occludin (A-C) and ZO-1 (D-F) compared with the baseline levels; G and H: Administering GM6001 to the MMP23B group improved the fluorescence intensity levels of occludin (G) and ZO-1 (H). Scale bar = 50 μm. ^cP < 0.001, ^dP < 0.0001. HG: High glucose.