Dexmedetomidine ameliorates diabetic intestinal injury by promoting the polarization of M2 macrophages through the MMP23B pathway

Figure 7 Macrophage clearance enhances intestinal function and improves the epithelium in diabetes mice. A-J: After 24 hours of treatment with clodronate liposomes, immunofluorescence analysis revealed a substantial decrease in ZO-1 and occludin levels; K and L: The immunofluorescence analysis demonstrated a notable elevation in the protein expression of occludin and ZO-1 following DB. Scale bar = 50 μm. ^aP < 0.05, ^cP < 0.001, ^dP < 0.0001. DB: Diabetes group; Cls: Clodronate liposomes.