Copyright
©The Author(s) 2024.
World J Diabetes. Sep 15, 2024; 15(9): 1932-1941
Published online Sep 15, 2024. doi: 10.4239/wjd.v15.i9.1932
Published online Sep 15, 2024. doi: 10.4239/wjd.v15.i9.1932
Figure 4 NPAS2 regulates KANK1expression.
A: Quantitative reverse transcriptase PCR (qRT-PCR) showed that NPAS2 overexpression increased the mRNA level of KANK1; B: Western blotting showed that NPAS2 overexpression enhanced the protein of KANK1; C: qRT-PCR showed knocking down NPAS2 with shRNA decreased the mRNA level of KANK1; D: Western blotting showed knocking down NPAS2 with shRNA decreased the protein of KANK1. aP < 0.01, bP < 0.001, cP < 0.0001. T2DM: Diabetes mellitus type 2.
- Citation: Yin YB, Ji W, Liu YL, Gao QH, He DD, Xu SL, Fan JX, Zhang LH. cNPAS2 induced β cell dysfunction by regulating KANK1 expression in type 2 diabetes. World J Diabetes 2024; 15(9): 1932-1941
- URL: https://www.wjgnet.com/1948-9358/full/v15/i9/1932.htm
- DOI: https://dx.doi.org/10.4239/wjd.v15.i9.1932