Corilagin alleviates podocyte injury in diabetic nephropathy by regulating autophagy via the SIRT1-AMPK pathway

Figure 4 Corilagin attenuates inflammatory infiltration in the kidneys of diabetic nephropathy mice. A: Representative images of immunohistochemical staining for IL-1β in kidney tissue of mice (magnification 200 ×); B-D: The levels of inflammatory factors (IL-1β, TNF-α, and IL-6) measured by ELISA in kidney tissue; E-G: Real-time quantitative PCR was carried out to determine the mRNA expression of IL-1β, TNF-α, and IL-6 in kidney tissue of mice. Data are presented as the mean ± SD (n = 8 in each group). ^aP < 0.001 vs control group; ^bP < 0.001 vs DN group. Cor: Corilagin; DN: Diabetic nephropathy.