Autoantibodies against beta cells to predict early insulin requirements in pediatric patients with clinically diagnosed type 2 diabetes

doi:10.4239/wjd.v15.i8.1717

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Aug 15, 2024 (publication date) through Nov 1, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Aug 15, 2024; 15(8): 1717-1725
Published online Aug 15, 2024. doi: 10.4239/wjd.v15.i8.1717

Table 6 Antibody titers according to insulin dependence

Variable	Total (n = 132)	No insulin dependence (n = 64)	Insulin dependent (n = 68)	P value
Anti-GAD65 (UI/mL)	11.0 (5-543)	6.8 (5-543)	12.0 (5-186)	0.69
Anti-IA2 (UI/mL)	14.6 (5-245)	8.45 (5-111)	21.6 (5-245)	0.6
Anti-Zn8T (UI/mL)	68.5 (15.9-178.2)	64.5 (47-74.5)	73.7 (15.9-178.2)	0.68

Median and minimum and maximum ranges. Mann–Witney U test. GAD65: Glutamic acid decarboxylase; IA2: Islet antigen 2; Zn8T: Zinc transporter 8.

Citation: Molina JM, Medina PG, Gomez RA, Herrera JR, Martínez NL, Hernández B, García Y. Autoantibodies against beta cells to predict early insulin requirements in pediatric patients with clinically diagnosed type 2 diabetes. World J Diabetes 2024; 15(8): 1717-1725
URL: https://www.wjgnet.com/1948-9358/full/v15/i8/1717.htm
DOI: https://dx.doi.org/10.4239/wjd.v15.i8.1717