Autoantibodies against beta cells to predict early insulin requirements in pediatric patients with clinically diagnosed type 2 diabetes

Table 2 Metabolic characteristics by insulin dependence, mean ± SD

Variable	Total (n = 132)	No insulin dependence (n = 64)	Insulin dependence (n = 68)	P value
TC (mg/dL)	175.9 ± 48.3	164.2 ± 37.4	186.9 ± 54.8	0.54
HDL-C (mg/dL)	44.1 ± 9.3	44.6 ± 7.5	43.6 ± 10.8	0.11
LDL-C (mg/dL)	107.1 ± 41.1	93.3 ± 28.8	118.3 ± 47.5	0.1
TG (mg/dL)	158.5 ± 21.1	148.5 ± 14.0	187.9 ± 19.9	0.18
Fasting glucose (mmol/L)	10.95 ± 0.55	7.62 ± 0.37	14.07 ± 0.51	0.08
HbA1c (%)	8.8 ± 2.9	6.7 ± 1.6	10.8 ± 2.3	0.001
Insulin (mUI/mL)	11.4 ± 7.7	12.7 ± 9.6	10.3 ± 5.0	0.3
C- peptide (ng/dL)	1.4 ± 1.3	2.53 ± 1.2	0.41 ± 0.36	0.001
HOMA-β	85.38 ± 16.6	125.5 ± 15.6	50.9 ± 16.8	0.022

TC: Total cholesterol; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein-cholesterol; TG: Triglycerides; HbA1c: Glycated hemoglobin A1c; HOMA-β: Homeostatic model assessment of beta cell function.