Glymphatic function and its influencing factors in different glucose metabolism states

Figure 2 The left-side\right-side\mean diffusion tensor image analysis method along the perivascular space index was evaluated. A: The diffusion tensor image analysis method along the perivascular space (DTI-ALPS) index of the left-side cerebral hemisphere in patients with type 2 diabetes mellitus (T2DM) was significantly lower than in the normal glucose metabolism (NGM) group; B: The DTI-ALPS index of the right cerebral hemisphere in patients with T2DM was significantly lower than that in the prediabetes group and the NGM group; C: The mean DTI-ALPS index of both cerebral hemispheres in patients with T2DM was significantly higher in the prediabetes and NGM groups. T2DM: Type 2 diabetes mellitus; NGM: Normal glucose metabolism; DTI-ALPS: Diffusion tensor image analysis method along the perivascular space; L-DTI-ALPS: Diffusion tensor image analysis method along the perivascular space index of the left cerebral hemisphere in prediabetes and type 2 diabetes mellitus; R-DTI-ALPS: Diffusion tensor image analysis method along the perivascular space index of the right cerebral hemisphere of prediabetes and type 2 diabetes mellitus; Mean-DTI-ALPS: Mean Diffusion tensor image analysis method along the perivascular space index in both cerebral hemispheres.