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©The Author(s) 2024.
World J Diabetes. Jun 15, 2024; 15(6): 1340-1352
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1340
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1340
Figure 4 The functions of growth hormone and adipocytokine after duodenal-jejunal bypass.
A: Serum concentrations of growth hormone (GH), adiponectin, leptin and adipsin; B and C: Western blot (B) and reverse transcription-qPCR (RT-qPCR; C) analysis of GH receptor (GHR), adiponectin, leptin and adipsin in visceral adipose tissue; D: Oil red O staining of mature adipocytes; E: Phase microscope of primary visceral adipocyte; F and G: Western blot (F) and RT-qPCR (G) analysis of GHR, adiponectin, leptin and adipsin in mature adipocytes; H and I: Western blot (H) and RT-qPCR (I) analysis of GHR, adiponectin, leptin and adipsin in primary visceral adipocyte; J: Immunofluorescent staining of GLUT4 and INSR of mature adipocytes with or without Adiponectin knockdown; K: Average optical density of Immunofluorescent staining. aP < 0.05, bP < 0.01, cP < 0.001. GH: Growth hormone; GHR: Growth hormone receptor; PA: Palmitic acid; HG: High glucose; DJB: Duodenal-jejunal bypass; SAT: Subcutaneous adipose tissue; VAT: Visceral adipose tissue; AOD: Average optical density.
- Citation: Liu ZT, Yang GW, Zhao X, Dong SH, Jiao Y, Ge Z, Yu A, Zhang XQ, Xu XZ, Cheng ZQ, Zhang X, Wang KX. Growth hormone improves insulin resistance in visceral adipose tissue after duodenal-jejunal bypass by regulating adiponectin secretion. World J Diabetes 2024; 15(6): 1340-1352
- URL: https://www.wjgnet.com/1948-9358/full/v15/i6/1340.htm
- DOI: https://dx.doi.org/10.4239/wjd.v15.i6.1340