X-Paste improves wound healing in diabetes via NF-E2-related factor/HO-1 signaling pathway

Figure 5 Andro accelerates diabetic foot ulcers wound healing by activating the NF-E2-related factor-2/HO-1 pathway. A: The representative images of 5-ethynyl-2’-deoxyuridine, tubule formation and TUNEL in wound tissue sections from different groups; B: The wound healing assay in 0 h and 24 h from different groups; C: Immunofluorescence staining of CD31 and alpha-smooth muscle actin (α-SMA); D and E: Western blot of NF-E2-related factor-2 and HO-1 expression in each group and quantification of Western blot results; F and G: CD31, VEGFA, and α-SMA expression in each group and quantification of Western blot results; H and I: Western blot analysis of interleukin-6 and tumour necrosis factor alpha expression and quantification of Western blot results. Statistical significance is expressed as ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001, P > 0.05 was not denoted.