X-Paste improves wound healing in diabetes via NF-E2-related factor/HO-1 signaling pathway

Figure 3 X-Paste promotes diabetic foot ulcers wound healing through the NF-E2-related factor-2/HO-1 pathway. A: The expression of NF-E2-related factor-2 (Nrf2) and HO-1 were measured by Western blot from skin wound tissues; B: Quantification of Western blot results; C: The protein of CD31, VEGFA, and alpha-smooth muscle actin were measured by Western blot from skin wound tissues; D: Quantification of Western blot results; E: Western blot analysis of interleukin-6 and tumour necrosis factor alpha protein expression; F: Quantification of Western blot results. Statistical significance is expressed as ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, P > 0.05 was not denoted. NC: Normal control; PBS: Phosphate-buffered saline; DM: Diabetic wound; XP: X-Paste; α-SMA: Alpha-smooth muscle actin; IL: Interleukin; TNF-α: Tumour necrosis factor alpha; Nrf2: NF-E2-related factor-2.