Therapeutic effects of Lingguizhugan decoction in a rat model of high-fat diet-induced insulin resistance

Figure 3 Lingguizhugan effectively preserves the morphology of pancreatic islet cells in insulin resistance rats. A: The pancreatic tissue sections were stained with HE to visualize the cellular structure (scale bar, 100 μm); B: IF analysis was performed to quantify the expression of insulin (red) and GLP-1R (green) in the pancreas; C: The expression of pancreatic GLP-1R was evaluated. The data are presented as the mean ± SD (n = 5 per group) and were statistically analyzed using ANOVA. ^bP < 0.01, high-fat diet (HFD)-Lingguizhugan vs HFD. ND: Normal diet; HFD: High-fat diet; LGZG: Lingguizhugan.