Therapeutic effects of Lingguizhugan decoction in a rat model of high-fat diet-induced insulin resistance

Figure 2 Lingguizhugan treatment significantly reduces hepatic steatosis in rats. A: Liver sections stained with H&E showed decreased fat accumulation in rats administered Lingguizhugan compared to high-fat diet (HFD)-fed rats (scale bar, 100 μm); B: Triglyceride; C: Total cholesterol; D: Low-density lipoprotein cholesterol E: Aspartate aminotransferase/alanine aminotransferase ratio were measured. The data are presented as the mean ± SD (n = 5 for each group) and were analyzed using a spherical test. Statistical comparisons were made compared to the HFD group, ^aP < 0.05, ^bP < 0.01. ND: Normal diet; HFD: High-fat diet; LGZG: Lingguizhugan; TC: Total cholesterol; TG: Triglyceride; LDL-C: Low-density lipoprotein cholesterol; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase ratio.