Evaluation of left ventricular systolic function in type 2 diabetes mellitus patients with and without peripheral vascular disease

doi:10.4239/wjd.v15.i6.1280

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jun 15, 2024; 15(6): 1280-1290
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1280

Table 1 Clinical parameters of patients among normal controls, type 2 diabetes mellitus patients without peripheral vascular disease and type 2 diabetes mellitus patients with peripheral vascular disease

Clinical parameters	Normal controls (n = 63)	T2DM without PVD (n = 65)	T2DM with PVD (n = 57)	P value
Age, yr	53.29 ± 7.55	54.75 ± 7.72	56.73 ± 7.76	0.053
Male, n (%)	31 (49)	38 (58)	38 (67)	0.103
Height, cm	164.84 ± 7.07	165.83 ± 8.61	164.20 ± 6.98	0.492
Weight, kg	63.56 ± 10.09	68.95 ± 11.76^a	67.32 ± 11.35	0.021
BMI, kg/m²	23.33 ± 2.91	24.97 ± 3.12	24.89 ± 3.40^a	0.005
BSA, m²	1.67 ± 0.16	1.74 ± 0.19	1.71 ± 0.17	0.054
SBP, mmHg	77.90 ± 0.57	82.17 ± 10.81^a	80.18 ± 10.58	0.001
DBP, mmHg	123.38 ± 11.12	132.77 ± 16.29^a	130.70 ± 17.30^a	0.049
HR, bpm	66.95 ± 8.61	75.58 ± 9.91^a	74.80 ± 8.20^a	< 0.001
HbA1c, %	5.48 ± 0.35	9.47 ± 2.39^a	9.94 ± 2.39^a	< 0.001
TC, mmol/L	4.53 ± 0.85	4.36 ± 1.06	4.55 ± 1.03	0.550
TG, mmol/L	1.30 (0.89, 1.80)	1.52 (0.93, 2.43)	1.64 (1.01, 2.07)	0.073
HDL-C, mmol/L	1.25 ± 0.33	1.08 ± 0.29	1.08 ± 0.34	0.013
LDL-C, mmol/L	2.65 ± 0.70	2.58 ± 0.84	2.70 ± 0.83	0.729
LPA, g/L	0.17 (0.09, 0.29)	0.12 (0.06, 0.32)	0.16 (0.09, 0.25)	0.772
FPG, mmol/L	4.99 (4.57, 5.28)	10.02 (7.44, 13.64)^a	10.25 (8.29, 14.07)^a	< 0.001
BUN, mmol/L	4.90 (3.60, 6.40)	5.65 (4.70, 6.58)	6.00 (4.70, 7.40)^a	0.015
SCr, μmol/L	65.00 (56.00, 76.00)	61.00 (51.75, 81.95)	61.70 (52.20, 73.00)	0.772
Medication (%)
ACEI/ARB	-	13 (20)	12 (21)
Calcium channel blocker	-	10 (15)	20 (35)
β-blocker	-	1 (2)	2 (4)
SGLT-2 inhibitor	-	14 (22)	19 (33)
Metformin	-	36 (55)	36 (63)
Insulin	-	41 (63)	42 (74)

^aP < 0.05, indicates significantly different when type 2 diabetes mellitus (T2DM) patients without peripheral vascular disease (PVD) or T2DM patients with PVD compared with the normal controls.

T2DM: Type 2 diabetes mellitus; BMI: Body mass index; BSA: Body surface area; SBP: Systolic blood pressure; DBP: Diastolic blood pressure. HR: Heart rate; FPG: Fasting plasma glucose; HbA1c: Glycated haemoglobin; TC: Total cholesterol; TG: Triglyceride; HDL-C: High density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; LPA: Lipoprotein a; BUN: Blood urea nitrogen; SCr: Serum creatinine.

Citation: Li GA, Huang J, Fan L. Evaluation of left ventricular systolic function in type 2 diabetes mellitus patients with and without peripheral vascular disease. World J Diabetes 2024; 15(6): 1280-1290
URL: https://www.wjgnet.com/1948-9358/full/v15/i6/1280.htm
DOI: https://dx.doi.org/10.4239/wjd.v15.i6.1280