Adipose-derived stem cells in diabetic foot care: Bridging clinical trials and practical application

doi:10.4239/wjd.v15.i6.1162

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Jun 15, 2024 (publication date) through Nov 12, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jun 15, 2024; 15(6): 1162-1177
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1162

Table 2 Comparison of adipose-derived stem cells administration methods for diabetic foot treatment

Method	Advantages	Disadvantages
Intravenous infusion	Targets multiple areas	Cells may get trapped in the lungs
Arterial injection	Direct delivery to the foot	Technically challenging and risk of blood vessel issues
Muscular injection	Directly reaches wound, good for poor blood flow, improves cell survival and nerve regeneration	Less effective for wounds away from muscle
Local injection	High cell concentration at the wound	Risk of uneven cell spread and clumping

Citation: Tseng SL, Kang L, Li ZJ, Wang LQ, Li ZM, Li TH, Xiang JY, Huang JZ, Yu NZ, Long X. Adipose-derived stem cells in diabetic foot care: Bridging clinical trials and practical application. World J Diabetes 2024; 15(6): 1162-1177
URL: https://www.wjgnet.com/1948-9358/full/v15/i6/1162.htm
DOI: https://dx.doi.org/10.4239/wjd.v15.i6.1162