Estrogen restores disordered lipid metabolism in visceral fat of prediabetic mice

Figure 5 Validation of estrogen protection of high-fat diet-induced disordered fat metabolism by RT-PCR in visceral adipose tissue of more calorie-dense high-fat diet-fed mice. A: Expression of fatty acid biosynthetic genes including Fasn, Acaca, and Oxam; B: Expression of fatty acid oxidative genes including Cpt1a, Cpt2, and Lipe. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. n = 5-6. HFD: High-fat diet; OVX: Ovariectomy; E2: 17β-estradiol; NS: Not significant.