Estrogen restores disordered lipid metabolism in visceral fat of prediabetic mice

doi:10.4239/wjd.v15.i5.988

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May 15, 2024 (publication date) through Feb 18, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. May 15, 2024; 15(5): 988-1000
Published online May 15, 2024. doi: 10.4239/wjd.v15.i5.988

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Figure 3 Estrogen restores high-fat diet-induced aberrant signaling pathways in visceral adipose tissue. A: Top ten significantly enriched pathways based on down-regulated genes by high-fat diet (HFD) + ovariectomy (OVX) compared to HFD + sham operation; B: Top ten significantly enriched pathways based on up-regulated genes by HFD + OVX + 17β-estradiol (E2) compared to HFD + OVX; C: Top ten significantly enriched pathways based on up-regulated genes by HFD + OVX compared to HFD + sham operation; D: Top ten significantly enriched pathways based on down-regulated genes by HFD + OVX + E2 compared to HFD + OVX. n = 3-4.

Citation: Liu SH, Shangguan ZS, Maitiaximu P, Li ZP, Chen XX, Li CD. Estrogen restores disordered lipid metabolism in visceral fat of prediabetic mice. World J Diabetes 2024; 15(5): 988-1000
URL: https://www.wjgnet.com/1948-9358/full/v15/i5/988.htm
DOI: https://dx.doi.org/10.4239/wjd.v15.i5.988