Polycytosine RNA-binding protein 1 regulates osteoblast function via a ferroptosis pathway in type 2 diabetic osteoporosis

Figure 1 Detection of osteoblast activity after the addition of different glucose concentrations at different time points. A: Osteoblasts considerably reduced in activity after 72 h in glucose concentrations ≥ 35 mmol/L; B: Osteoblasts treated with high glucose (HG) combined with Fer-1 showed increased activity compared with those in the HG group. Data are presented as mean ± SD. ^aP < 0.05 vs control; ^cP < 0.05 vs HG. HG: High glucose.