Enzyme-linked immunosorbent assay of 3 Screen Islet Cell Autoantibody in patients with autoimmune thyroid disease

Figure 6 Comparison 3 Screen Islet Cell Autoantibody titer between glutamic acid decarboxylase autoantibody-positive and -negative patients. 3 Screen Islet Cell Autoantibody titers were significantly higher in glutamic acid decarboxylase 65 autoantibody (GADA)-positive patients than in GADA-negative patients, and there was no significant difference between multiple individual autoantibody-positive patients and patients with GADA alone. The circle, diamond, and triangle symbols indicate autoimmune thyroid disease (AITD) with type 1 diabetes, AITD with type 2 diabetes, and AITD without diabetes, respectively. Multiple: GADA-positive patients with insulinoma-associated antigen-2 autoantibodies and/or zinc transporter 8 autoantibodies; Single: GADA single-positive ^aP < 0.005 vs GADA-negative. GADA: Glutamic acid decarboxylase 65 autoantibodies; 3 Screen ICA: 3 Screen Islet Cell Autoantibody.