Efficacy of Huangma Ding or autologous platelet-rich gel for the diabetic lower extremity arterial disease patients with foot ulcers

Table 1 Baseline characteristics of patients in each group (mean ± SD)

Parameter	Group A	Group B	Group C	P value
n	62	38	55
Age (yr)	60.83 ± 11.28	63.26 ± 10.94	62.89 ± 7.71	0. 401
Duration (yr)	9.81 ± 8.66	9.34 ± 6.68	7.31 ± 5.28	0.148
Weight (kg)	61.28 ± 7.47	60.60 ± 10.90	58.33 ± 8.52	0.178
Height (m)	1.63 ± 0.07	1.60 ± 0.10	1.61 ± 0.06	0.255
FPG (mmol/L)	8.45 ± 2.21	7.38 ± 3.18	8.40 ± 4.25	0.239
White blood cells	8.34 ± 2.66	7.51 ± 1.42	8.24 ± 2.30	0.181
Neutrophils	5.67 ± 2.61	4.85 ± 1.38	5.65 ± 1.99	0.134
HbA1c (%)	8.46 ± 1.66	8.00 ± 1.52	8.61 ± 1.71	0.203
LDL (mmol/L)	2.60 ± 0.70	2.56 ± 0.57	2.56 ± 0.52	0.932
HDL (mmol/L)	1.00 ± 0.30	1.10 ± 0.39	1.00 ± 0.18	0.240
TC (mmol/L)	4.62 ± 1.00	4.45 ± 0.97	4.58 ± 0.81	0.661
TG (mmol/L)	1.38 ± 0.52	1.49 ± 0.68	1.58 ± 0.56	0.233
Creatinine (mmol/L)	78.73 ± 18.62	84.69 ± 26.02	81.03 ± 20.36	0.398
History of smoking (yr)	7.45 ± 11.73	10.47 ± 16.43	7.76 ± 15.00	0.552
Hypertension Duration (yr)	5.11 ± 9.01	3.74 ± 5.97	3.53 ± 4.72	0.425
Uric acid (µmol/L)	308.61 ± 83.34	324.05 ± 98.75	338.05 ± 101.20	0.240
Diabetic retinopathy	24.19%	18.42%	16.36%	0.555
Diabetic peripheral neuropathy	96.77%	86.84%	87.27%	0.121
Diabetic kidney disease	41.94%	39.47%	50.91%	0.485
Coronary heart disease	9.68%	2.63%	1.27%	0.245
PAD	100%	100%	100%	1.000
Metformin	93.55%	89.47%	83.64%	0.233
Insulin secretagogues	14.52%	10.53%	18.18%	0.596
Acarbose	25.81%	23.68%	16.36%	0.453
Insulin	83.87%	86.84%	90.91%	0.530
ACEI/ARB	40.32%	47.37%	56.36%	0.225
CCB	27.42%	26.32%	27.27%	0.992
Diuretic	3.23%	7.89%	1.82%	0.314
SBP (mmHg)	134.01 ± 17.86	131.82 ± 16.67	137.84 ± 13.52	0.187
DBP (mmHg)	80.71 ± 9.49	78.90 ± 10.37	78.65 ± 10.84	0.503

FPG: Fasting blood glucose; HbA1c: Glycosylated hemoglobin; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; TC: Total cholesterol; TG: Triglyceride; PAD: Peripheral artery disease; ACEI/ARB: Angiotensin-converting enzyme inhibitors/angiotensin II receptor blocker; CCB: Calcium channel blocker; SBP: Systolic blood pressure; DBP: Diastolic blood pressure.