Long-term effects of gestational diabetes mellitus on the pancreas of female mouse offspring

Figure 1 Experimental design, body weight, and blood glucose levels of female offspring born from control dams or dams with gestational diabetes mellitus. A: Diagram showing the experimental design and timeline; B and C: Female offspring born from dams treated with streptozotocin during pregnancy did not show significant changes in body weight or blood glucose compared to offspring born from dams treated with vehicle as controls; D: Scheme showing the region selected for quantification (splenic pancreas; square) of the neuronal, vascular, and inflammatory changes using immunohistochemistry and confocal microscopy. Data are shown as mean ± SEM, n = 5 per group. STZ: Streptozotocin; VEH: Vehicle.