Novel insights into immune-related genes associated with type 2 diabetes mellitus-related cognitive impairment

Figure 3 Identification of module genes via Weighted Gene Co-Expression Network Analysis. A and B: The soft threshold β = 3 is chosen as the result of the combined analysis of scale independence and average connectivity; C: Different colors represent gene co-expression modules in the gene tree; D: Heatmap illustrating the correlation between modules and type 2 diabetes mellitus (T2DM). There is a significant correlation between the brown module and T2DM; E: The brown module contains 974 genes, and the scatter diagram shows the correlation between membership in the brown module and gene significance for the group; F: Analysis of gene enrichment in the brown module for functional purposes.