Potential application of Nardostachyos Radix et Rhizoma-Rhubarb for the treatment of diabetic kidney disease based on network pharmacology and cell culture experimental verification

Figure 6 Effect of NardostachyosRadix etRhizoma-rhubarb drug pair on AGE-RAGE signaling pathway in TCMK-1 cells. A, B, C, and E: Protein expression of BAX, BCL-2, Caspase9, and Caspase3; D and F: Expression of STAT3 and p-STAT3 protein. CON: Control group; MOD: Model group; NRDP: Nardostachyos Radix et Rhizoma-rhubarb drug pair. ^aP <0.001, ^bP < 0.001, ^cP <0.01, ^dP < 0.05, ^eP <0.05.