Potential application of Nardostachyos Radix et Rhizoma-Rhubarb for the treatment of diabetic kidney disease based on network pharmacology and cell culture experimental verification

Figure 5 Effect of NardostachyosRadix etRhizoma-rhubarb drug pair on cellular phenotype of TCMK-1 cells. A and B: Nardostachyos Radix et Rhizoma-rhubarb drug pair (NRDP) reduces the activity of TCMK-1 cells; C: Effect of NRDP on the cell cycle of TCMK-1 cells; D: Effect of NRDP on apoptosis of TCMK-1 cells. CON: Control group; MOD: Model group; NRDP: Nardostachyos Radix et Rhizoma-rhubarb drug pair; IC₅₀: Half maximal inhibitory concentration. ^aP < 0.001, ^bP < 0.001, ^cP <0.01.