Comparative efficacy of sodium glucose cotransporter-2 inhibitors in the management of type 2 diabetes mellitus: A real-world experience

doi:10.4239/wjd.v15.i3.463

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Mar 15, 2024 (publication date) through Nov 3, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Mar 15, 2024; 15(3): 463-474
Published online Mar 15, 2024. doi: 10.4239/wjd.v15.i3.463

Table 2 Follow-up metabolic/clinical/lab parameters for dapagliflozin

Clinical/lab/parameter	Baseline, median (IQR; n)	6 months F/U, median (IQR; n)	12 months, median (IQR; n)	Latest, median (IQR; n)	P value (baseline vs latest)
HbA1c	78 (25.3; 227)	68 (25; 204)^a	66.5 (22.8; 190)^b	69 (24; 191)	< 0.001
Weight	101 (29.5; 198)	95.4 (28.2; 150)^a	95.9 (29.2; 144)^a	92.2 (25.6; 93)	< 0.001
BMI	33.7 (6.6; 81)	-	-	33.9 (6.38; 44)	0.002
Systolic BP	145 (21.3; 185)	-	142 (23; 159)	142 (23.3; 112)	0.080
Diastolic BP	84 (14; 185)	-	80 (14; 159)^b	80 (19.3; 112)	< 0.001
Albuminuria (> 3 mmol/mg)	5.2 (17.4; 39)	3 (14.9; 24)^a	2.1 (6.38; 18)^a	4.4 (11.9; 30)	0.063

^aP < 0.05.

^bP < 0.01.

BMI: Body mass index; BP: Blood pressure; HbA1c: Glycated hemoglobin; IQR: Interquartile range.

Citation: Islam L, Jose D, Alkhalifah M, Blaibel D, Chandrabalan V, Pappachan JM. Comparative efficacy of sodium glucose cotransporter-2 inhibitors in the management of type 2 diabetes mellitus: A real-world experience. World J Diabetes 2024; 15(3): 463-474
URL: https://www.wjgnet.com/1948-9358/full/v15/i3/463.htm
DOI: https://dx.doi.org/10.4239/wjd.v15.i3.463