Duodenal-jejunal bypass improves hypothalamic oxidative stress and inflammation in diabetic rats via glucagon-like peptide 1-mediated Nrf2/HO-1 signaling

Figure 6 Duodenal jejunal bypass surgery improves diabetes-induced hypothalamic cell apoptosis in type 2 diabetes mellitus rats. A: The quantitative real-time (qRT)-PCR results of Caspase-3 expression; B: The qRT-PCR results of Bcl-2 expression; C: Expression levels of apoptosis-related proteins in the hypothalamus by Western blotting; D: The quantitative densitometric analysis of apoptosis-related proteins. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. T2DM: Type 2 diabetes mellitus; DJB: Duodenal jejunal bypass.